Methods | OECD


The Organisation for Economic Co-operation and Development (OECD) are globally recognized guidelines for safety testing and assessing the potential effects of chemicals on human health.

OECD 437

Bovine Corneal Opacity and Permeability (BCOP) Test Method for Identifying Ocular Corrosives/Severe Irritants and Substances not Classified as Irritants The Bovine Corneal Opacity and Permeability (BCOP) test method is an in-vitro test method that can…
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Dermal OECD 439

In-Vitro Skin Irritation: Reconstructed Human Epidermis Test Method This method is based on reconstructed human epidermis, which closely mimics the properties of the upper layers of the human skin. Cell viability is measured by enzymatic…
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Dermal OECD 431

In-Vitro Skin Corrosion: Human Skin Model Test In this method, the test material (solid or liquid) is applied to a three-dimensional human skin model and corrosive materials are identified by their ability to produce a…
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OECD 435

This method describes an in vitro membrane barrier test method that is used to identify corrosive substances. It utilizes an artificial membrane designed to respond to corrosive substances in a manner similar too animal skin.…
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OECD 492

This method utilizes human cornea-like epithelium which closely mimics the basic properties of the human corneal epithelium. The test evaluates the ability of a test chemical to induce cytotoxicity in a tissue construct, as measured…
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