The Organisation for Economic Co-operation and Development (OECD) are globally recognized guidelines for safety testing and assessing the potential effects of chemicals on human health.
Organization for Economic Co-operation and Development (OECD) updated “Guidance Document on an Integrated Approach on Testing and Assessment (IATA) for Serious Eye Damage and Eye Irritation”. The updated document replaces "sequential testing strategy" with IATA for serious eye damage and eye irritation hazard identification and provides guidance on how and when to integrate existing and/or newly generated information for decision making, including decisions on the need for further testing or final decisions on classification and labelling regarding the potential eye hazard of test chemicals. The guidance document describes the elements (modules) of IATA for identification of eye hazard. It is notable that multiple testing methods developed using in vitro and ex vivo models1 allow for eye hazard classification and labelling without the need of in vivo testing (Draize test method, the US FHSA method 16CFR 1500.42, and OECD TG 405). The table below presents strategy of Integrated Approach on Testing and Assessment for Serious Eye Damage and Eye Irritation.