The U.S. Pharmacopeia describes in General Chapter 51, the assay they recommend for testing preservative efficacy. The USP divides products into four categories:
Category 1 - Injectable, emulsion, otic, sterile nasal and ophthalmic products made in aqueous bases
Category 2 – Topically used products made with aqueous bases or vehicles; nonsterile nasal products and emulsions, including those applied to the mucous membranes
Category 3 – Oral products other than antacids, made with aqueous bases or vehicles
Category 4 – Antacids made with an aqueous base
Each category of products is challenged with five microorganisms independently and samples are taken at intervals specified for each category throughout 28 days.
Scientists in our In-Vitro testing labs are well trained on ASTM, AATCC, AOAC, CLSI and EN standard methods. The efficacy testing services of this laboratory include MIC/MBC, ...Learn More