OECD 437

OECD 437

Bovine Corneal Opacity and Permeability (BCOP) Test Method for Identifying Ocular Corrosives/Severe Irritants and Substances not Classified as Irritants

The Bovine Corneal Opacity and Permeability (BCOP) test method is an in-vitro test method that can be used, under certain circumstances and with specific limitations for eye hazard classification and labeling of substances. The purpose of this Test Guideline is to describe the procedures used to evaluate the potential ocular corrosivity or severe irritancy of a test substance as measured by its ability to induce opacity and increased permeability in an isolated bovine cornea. 

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In-Vitro Laboratory

Scientists in our In-Vitro testing labs are well trained on ASTM, AATCC, AOAC, CLSI, and EN standard methods. The efficacy testing services of this laboratory include MIC/MBC, biofilm prevention and removal, time-kill kinetics, clean room disinfectant validation, zone of inhibition and custom efficacy studies for disinfectants, antimicrobials and other products requiring EPA registrations and FDA 510(k) submissions. Studies in…

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Virology Laboratory

BioScience Laboratories assists clients with new product development, R&D projects, marketing claims, and supporting EPA, FDA, EU, and Health Canada label claims. Combining our virology capabilities with over 23 years of experience in conducting GLP and GCP compliant studies, we can offer a start-to-finish solution. Our virology laboratory personnel are well-trained on the…

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