OECD 435 | Bioscience Labs

OECD 435

OECD 435

In Vitro Membrane Barrier Test Method for Skin Corrosion

This method describes an in vitro membrane barrier test method that is used to identify corrosive substances. It utilizes an artificial membrane designed to respond to corrosive substances in a manner similar to animal skin. The in vitro membrane barrier test method is most often used to test solids, emulsions and liquids.  However, aqueous substances with a pH in the range of 4.5 to 8.5 often do not qualify for testing. This test allows the identification of corrosive chemical substances and mixtures and allows for categorizing different degrees of corrosiveness.


In-Vitro Testing Laboratory

Scientists in our In-Vitro testing labs are well trained on ASTM, AATCC, AOAC, CLSI and EN standard methods. The efficacy testing services of this laboratory include MIC/MBC, biofilm prevention and removal, time-kill kinetics, clean room disinfectant validation, zone of inhibition and custom efficacy studies for disinfectants, antimicrobials and other products requiring EPA registrations and FDA 510(k) submissions. Studies in our…

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